from opentrons import types
metadata = {
'protocolName': 'HTGAA Opentrons Lab',
'author': 'HTGAA',
'source': 'HTGAA 2022',
'apiLevel': '2.20'
}
##############################################################################
### Robot deck setup constants - don't change these
##############################################################################
TIP_RACK_DECK_SLOT = 9
COLORS_DECK_SLOT = 6
AGAR_DECK_SLOT = 5
PIPETTE_STARTING_TIP_WELL = 'A1'
well_colors = {
'A1' : 'Red',
'B1' : 'Yellow',
'C1' : 'Green',
'D1' : 'Cyan',
'E1' : 'Blue' # if in a 24-well plate, this needs to be moved to e.g. D2
}
def run(protocol):
##############################################################################
### Load labware, modules and pipettes
##############################################################################
# Tips
tips_20ul = protocol.load_labware('opentrons_96_tiprack_20ul', TIP_RACK_DECK_SLOT, 'Opentrons 20uL Tips')
# Pipettes
pipette_20ul = protocol.load_instrument("p20_single_gen2", "right", [tips_20ul])
# Modules
temperature_module = protocol.load_module('temperature module gen2', COLORS_DECK_SLOT)
# Temperature Module Plate
temperature_plate = temperature_module.load_labware('opentrons_96_aluminumblock_generic_pcr_strip_200ul',
'Cold Plate')
# Choose where to take the colors from
color_plate = temperature_plate
# Agar Plate
agar_plate = protocol.load_labware('htgaa_agar_plate', AGAR_DECK_SLOT, 'Agar Plate') ## TA MUST CALIBRATE EACH PLATE!
# Get the top-center of the plate, make sure the plate was calibrated before running this
center_location = agar_plate['A1'].top()
pipette_20ul.starting_tip = tips_20ul.well(PIPETTE_STARTING_TIP_WELL)
##############################################################################
### Patterning
##############################################################################
###
### Helper functions for this lab
###
# pass this e.g. 'Red' and get back a Location which can be passed to aspirate()
def location_of_color(color_string):
for well,color in well_colors.items():
if color.lower() == color_string.lower():
return color_plate[well]
raise ValueError(f"No well found with color {color_string}")
# For this lab, instead of calling pipette.dispense(1, loc) use this: dispense_and_jog(pipette, 1, loc)
def dispense_and_jog(pipette, volume, location):
"""
Dispense and then move up 5mm and back down to shake all dispensed fluid off the tip;
this also ensures it's not moving laterally before the dispense is done.
"""
assert(isinstance(volume, (int, float)))
pipette.dispense(volume, location)
currLoc = pipette._get_last_location_by_api_version()
pipette.move_to(currLoc.move(types.Point(z=5)))
pipette.move_to(currLoc)
###
### YOUR CODE HERE to create your design
###
# H
cursor = center_location.move(types.Point(x=-35.5, y = 12))
pipette_20ul.pick_up_tip()
pipette_20ul.aspirate(20, location_of_color('Red'))
for i in range(12):
dispense_and_jog(pipette_20ul, 1, cursor)
dispense_and_jog(pipette_20ul, 1, cursor.move(types.Point(x=2)))
if i == 9:
pipette_20ul.aspirate(10, location_of_color('Red'))
cursor = cursor.move(types.Point(y =-2))
cursor = cursor.move(types.Point(x=4, y=14))
for i in range(3):
dispense_and_jog(pipette_20ul, 1, cursor)
dispense_and_jog(pipette_20ul, 1, cursor.move(types.Point(y=-2)))
cursor = cursor.move(types.Point(x =2))
cursor = cursor.move(types.Point(y=10))
pipette_20ul.aspirate(20, location_of_color('Red'))
for i in range(12):
dispense_and_jog(pipette_20ul, 1, cursor)
dispense_and_jog(pipette_20ul, 1, cursor.move(types.Point(x=2)))
cursor = cursor.move(types.Point(y =-2))
if i == 9:
pipette_20ul.aspirate(4, location_of_color('Red'))
cursor = cursor.move(types.Point(x=4, y=24))
pipette_20ul.drop_tip()
pipette_20ul.pick_up_tip()
# T
pipette_20ul.aspirate(16, location_of_color('Yellow'))
for i in range(8):
dispense_and_jog(pipette_20ul, 1, cursor)
dispense_and_jog(pipette_20ul, 1, cursor.move(types.Point(y=-2)))
cursor = cursor.move(types.Point(x =2))
cursor = cursor.move(types.Point(x=-10, y=-4))
pipette_20ul.aspirate(20, location_of_color('Yellow'))
for i in range(10):
dispense_and_jog(pipette_20ul, 1, cursor)
dispense_and_jog(pipette_20ul, 1, cursor.move(types.Point(x=2)))
cursor = cursor.move(types.Point(y =-2))
pipette_20ul.drop_tip()
pipette_20ul.pick_up_tip()
# G
cursor = cursor.move(types.Point(x=10, y=2))
pipette_20ul.aspirate(20, location_of_color('Green'))
for i in range(12):
dispense_and_jog(pipette_20ul, 1, cursor)
dispense_and_jog(pipette_20ul, 1, cursor.move(types.Point(x=2)))
cursor = cursor.move(types.Point(y =2))
if i == 9:
pipette_20ul.aspirate(14, location_of_color('Green'))
cursor = cursor.move(types.Point(x=4, y=-2))
for i in range(5):
dispense_and_jog(pipette_20ul, 1, cursor)
dispense_and_jog(pipette_20ul, 1, cursor.move(types.Point(y=-2)))
cursor = cursor.move(types.Point(x =2))
cursor = cursor.move(types.Point(x=-4, y=-12))
pipette_20ul.aspirate(18, location_of_color('Green'))
for i in range(6):
dispense_and_jog(pipette_20ul, 1, cursor)
dispense_and_jog(pipette_20ul, 1, cursor.move(types.Point(x=2)))
cursor = cursor.move(types.Point(y=-2))
cursor = cursor.move(types.Point(x=-2, y=4))
for i in range(3):
dispense_and_jog(pipette_20ul, 1, cursor)
dispense_and_jog(pipette_20ul, 1, cursor.move(types.Point(y=-2)))
cursor = cursor.move(types.Point(x =-2))
# A
pipette_20ul.drop_tip()
pipette_20ul.pick_up_tip()
cursor = cursor.move(types.Point(x=12, y=-2))
pipette_20ul.aspirate(20, location_of_color('Cyan'))
for i in range(12):
dispense_and_jog(pipette_20ul, 1, cursor)
dispense_and_jog(pipette_20ul, 1, cursor.move(types.Point(x=2)))
cursor = cursor.move(types.Point(y =2, x=0.4))
if i == 9:
pipette_20ul.aspirate(4, location_of_color('Cyan'))
cursor = cursor.move(types.Point(x=2, y=-2))
pipette_20ul.aspirate(20, location_of_color('Cyan'))
for i in range(12):
dispense_and_jog(pipette_20ul, 1, cursor)
dispense_and_jog(pipette_20ul, 1, cursor.move(types.Point(x=2)))
cursor = cursor.move(types.Point(y =-2, x=0.4))
if i == 9:
pipette_20ul.aspirate(4, location_of_color('Cyan'))
cursor = cursor.move(types.Point(x=4, y=2))
# A
pipette_20ul.drop_tip()
pipette_20ul.pick_up_tip()
pipette_20ul.aspirate(20, location_of_color('Blue'))
for i in range(12):
dispense_and_jog(pipette_20ul, 1, cursor)
dispense_and_jog(pipette_20ul, 1, cursor.move(types.Point(x=2)))
cursor = cursor.move(types.Point(y =2, x=0.4))
if i == 9:
pipette_20ul.aspirate(4, location_of_color('Blue'))
cursor = cursor.move(types.Point(x=2, y=-2))
pipette_20ul.aspirate(20, location_of_color('Blue'))
for i in range(12):
dispense_and_jog(pipette_20ul, 1, cursor)
dispense_and_jog(pipette_20ul, 1, cursor.move(types.Point(x=2)))
cursor = cursor.move(types.Point(y =-2, x=0.4))
if i == 9:
pipette_20ul.aspirate(4, location_of_color('Blue'))
pipette_20ul.drop_tip()